Orioles vs. Blue Jays prediction and odds for Friday, May 19 (O's are live underdogs)

The Toronto Blue Jays are in the midst of a streak of series against AL East opponents.

This weekend, they'll host the Baltimore Orioles, who are surprising baseball fans and bettors with stellar play for the second straight season.

The Tampa Bay Rays are well in front of the AL East, but it's the Orioles who are in second place, not only in the division, but in the entire American League.

Let's dive into the betting odds for Game 1 of this weekend AL East series.

Orioles vs. Blue Jays odds, run line, and total

Orioles vs. Blue Jays prediction and pick

Yusei Kikuchi has a 4-0 record this year, but he's about to meet his match in the Baltimore Orioles.

The O's have been dominating left-handed pitchers this season, sporting an .806 OPS against lefties, which is the fifth best mark in Major League Baseball.

Kikuchi is also due for some regression. Sure, his 3.89 ERA is strong, but a 5.46 FIP (Field Independent Pitching) is concerning to say the least. It's also certainly worth noting that he had an 8.10 ERA in three starts and six appearances against Baltimore last season. Yikes.

You never know what you're going to get out of a start from Kyle Gibson, but if he can survive, the Orioles will get to turn to their red hot bullpen that has been one of the best in the Majors in the month of May. So far this month, they have a bullpen ERA of 2.96, significantly better than the Blue Jays bullpen has is sitting at an ERA of 3.86 in May.

At +140, the Orioles provide a great opportunity to bet on an underdog on Friday.

Game odds refresh periodically and are subject to change.